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Mahmoud Abdalghany Mahmoud Mahdy

Faculty pharmacy - Department Pharmaceutics Department

BSc In NULL, [1979]
PhD In NULL, [1986]
(Plasma protein link with some anti-inflammatory drugs)

قائم بالعمل

Academic Jobs

معيد : 12/12/1979
Doctor Assisant : 10/4/1983
Doctor : 14/5/1986
Professor Assisant : 22/9/1992
Professor : 24/6/2003
Professor Emeritus : 1/8/2016

Publications

1 - Encapsulation in a rapid-release liposomal formulation enhances the anti-tumor efficacy of pemetrexed in a murine solid mesothelioma-xenograft model (2016).

2 - INTRANASAL MICROEMULGEL AS SURROGATE CARRIER TO ENHANCE LOW ORAL BIOAVAILABILITY OF SULPIRIDE (2016).

3 - Sulpiride microemulsions as antipsychotic nasal drug delivery systems: In-vitro and pharmacodynamic study (2016).

4 - Alpha 1 Antitrypsin Inhibits Dendritic Cell Activation and Attenuates Nephritis in a Mouse Model of Lupus (2016).

5 - A Novel Strategy to Increase the Yield of Exosomes (Extracellular Vesicles) for an Expansion of Basic Research (2018).

6 - Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways (2018).

7 - Liposome co-incubation with cancer cells secreted exosomes (extracellular vesicles) with different proteins expressions and different uptake pathways. (2018).

8 - Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues (2019).

9 - Design and characterization of intra-oral fast dissolving tablets containing diacerein-solid dispersion (2020).

10 - Development, optimization, and evaluation of PEGylated brucine-loaded PLGA nanoparticles (2020).

11 - Brucine PEGylated nanoemulsion: In vitro and in vivo evaluation (2021).

12 - Basic Concepts of Nanoemulsion and its Potential application in Pharmaceutical, Cosmeceutical and Nutraceutical fields (2021).

13 - Optimization of mirtazapine loaded into mesoporous silica nanostructures via Box-Behnken design: in-vitro characterization and in-vivo assessment (2022).

14 - A new modality in targeted delivery of epirubicin for tumor theranosis based on PEGylated silver nanoparticles: Design, radiolabeling and bioevaluation (2022).

15 - Improving the tumor targeting efficiency of epirubicin via conjugation with radioiodinated poly (vinyl alcohol)-coated silver nanoparticles (2022).

16 - The Exploitation of pH-Responsive Eudragit-Coated Mesoporous Silica Nanostructures in the Repurposing of Terbinafine Hydrochloride for Targeted Colon Cancer Inhibition: Design Optimization, In Vitro Characterization, and Cytotoxicity Assessment (2023).

17 - Design of mirtazapine solid dispersion with different carriers’ systems: optimization, in vitro evaluation, and bioavailability assessment (2023).

18 - Clarithromycin-tailored cubosome: A sustained release oral nano platform for evaluating antibacterial, anti-biofilm, anti-inflammatory, anti-liver cancer, biocompatibility, ex-vivo and in-vivo studies (2024).

19 - Effective tailoring of cefepime into bilosomes: A promising nanoplatform for enhancing oral absorption, extending half-life, and evaluating biocompatibility, antibacterial, anti-biofilm, anti-breast cancer activity, ex-vivo, and in-vivo studies (2025).

20 - Tailoring of spanlastics for promoting transdermal delivery of irbesartan: In vitro characterization, ex vivo permeation and in vivo assessment (2024).

Research Area