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Curriculum Vitae
Tarek Mohamed Salah Rashad
Faculty pharmacy - Department Pharmaceutical Organic Chemistry Department
NULL
Scientific degrees
BSc In NULL, [2000]
MSc In NULL, [2007]
(pharmacutical organic chemistry)
PhD In NULL, [2012]
الحالة الوظيفية الحالية :
معار
Academic Jobs
معيد : 26/11/2001
Doctor Assisant : 23/9/2007
Doctor : 27/3/2012
Professor Assisant : 29/5/2018
Professor : 31/10/2023
Publications
1 -
Synthesis of certain 1,2,3,-Benzotriazine Derivatives of Pharmaceutical Interest
2 -
Chemical ligation of S-acylated cysteine peptides to form native peptides via 5-, 11-, and 14-membered cyclic transition states. (2011).
3 -
Synthesis of Coumarin Conjugates of Biological Thiols for Fluorescent Detection and Estimation. (2011).
4 -
Benzotriazole reagents for the syntheses of Fmoc, Boc and Alloc-Protected Amino Acids (2011).
5 -
Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41 (2011).
6 -
Cysteinoyl- and Cysteine-containing Dipeptidoylbenzotriazoles with Free Sulfhydryl groups: (2012).
7 -
Synthesis, molecular modeling and anti-inflammatory screening of new 1,2,3-Benzotriazinone Derivatives (2012).
8 -
Efficient synthesis of N-acylbenzotriazoles using tosyl chloride: en route to suberoylanilide hydroxamic acid (SAHA). (2016).
9 -
Benzotriazole-Mediated Synthesis and Antibacterial Activity of Novel N-Acylcephalexins. (2016).
10 -
Green and Catalyst-Free Synthesis of Olsalazine Analogs (2016).
11 -
Synthesis and Antiviral Bioassay of New Diphenyl Ether-based Compounds (2016).
12 -
Synthesis and Anticancer Studies of Novel N-Benzyl pyridazinone Derivatives (2017).
13 -
Synthesis, antibacterial properties and 2D-QSAR studies of quinolonetriazole conjugates (2018).
14 -
Synthesis, Anticonvulsant Activity and Cytotoxicity of Novel Valproic Acid Derivatives (2017).
15 -
Synthesis and Anticancer Studies of Novel N-Benzyl Pyridazinone Derivatives (2017).
16 -
Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors (2019).
17 -
Novel benzenesulfonamide and 1,2-benzisothiazol-3(2H)-one-1,1-dioxide derivatives as potential selective COX-2 inhibitors (2019).
18 -
Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids. (2019).
19 -
Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone-dichloroacetic acid hybrids. (2019).
20 -
The Anticancer Activity for the Bumetanide-Based Analogs via Targeting the Tumor-Associated Membrane-Bound Human Carbonic Anhydrase-IX Enzyme (2020).
21 -
Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold (2020).
22 -
Design, synthesis and anticancer activity of novel valproic acid conjugates with improved histone deacetylase (HDAC) inhibitory activity (2020).
23 -
Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy (2020).
24 -
Potent Quinoline-Containing Combretastatin A-4 Analogues: Design, Synthesis, Antiproliferative, and Anti-Tubulin Activity (2020).
25 -
N‑Acylbenzotriazole: convenient approach for protecting group‑free monoacylation of symmetric diamines (2020).
26 -
Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone–dichloroacetic acid hybrids (2020).
27 -
Design, synthesis and biological evaluation of novel 5-((substituted quinolin-3-yl/1-naphthyl) methylene)-3-substituted imidazolidin-2,4-dione as HIV-1 fusion inhibitors (2020).
28 -
An Efficient Greener Approach for N-Acylation of Amines in Water Using Benzotriazole Chemistry (2020).
29 -
In Vitro Antimycobacterial Activity and Physicochemical Characterization of Diaryl Ether Triclosan Analogues as Potential InhA Reductase Inhibitors (2020).
30 -
Efficient Synthesis and Computational Studies of Useful Guanylating Agents: 1H-Benzotriazole-1-carboximidamides (2020).
31 -
Repurposing anti-diabetic drug “Sitagliptin” as a novel virulence attenuating agent in Serratia marcescens (2020).
32 -
Repurposing Anti-diabetic Drugs to Cripple Quorum Sensing in Pseudomonas aeruginosa (2020).
33 -
Xylitol Inhibits Growth and Blocks Virulence in Serratia marcescens (2021).
34 -
Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition (2021).
35 -
Alteration of Salmonella enterica Virulence and Host Pathogenesis through Targeting sdiA by Using the CRISPR-Cas9 System (2021).
36 -
Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors (2022).
37 -
Novel Sunifiram-carbamate hybrids as potential dual acetylcholinesterase inhibitor and NMDAR coagonist: simulation-guided analogue design and pharmacological screening (2022).
38 -
Uracil as a Zn-Binding Bioisostere of the Allergic Benzenesulfonamide in the Design of Quinoline–Uracil Hybrids as Anticancer Carbonic Anhydrase Inhibitors (2022).
39 -
Design, Synthesis, In Vitro Anticancer Evaluation and Molecular Modelling Studies of 3,4,5-Trimethoxyphenyl-Based Derivatives as Dual EGFR/HDAC Hybrid Inhibitors (2021).
40 -
New Multi-Targeted Antiproliferative Agents: Design and Synthesis of IC261-Based Oxindoles as Potential Tubulin, CK1 and EGFR Inhibitors (2021).
41 -
Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer (2021).
42 -
Design, synthesis and pharmacological screening of novel renoprotective methionine-based peptidomimetics: Amelioration of cisplatin-induced nephrotoxicity (2021).
43 -
New quinoline-triazole conjugates: Synthesis, and antiviral properties against SARS-CoV-2 (2021).
44 -
Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction (2021).
45 -
Novel 1,2,4-triazine-quinoline hybrids: The privileged scaffolds as potent multi-target inhibitors of LPS-induced inflammatory response via dual COX-2 and 15-LOX inhibition (2021).
46 -
Novel 1,2,4-oxadiazole-chalcone/oxime hybrids as potential antibacterial DNA gyrase inhibitors: Design, synthesis, ADMET prediction and molecular docking study (2021).
47 -
Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect (2021).
48 -
Efficient Synthesis and Computational Studies of Useful Guanylating Agents: 1H-Benzotriazole-1-carboximidamides (2020).
49 -
N‑Acylbenzotriazole: convenient approach for protecting group‑free monoacylation of symmetric diamines (2020).
50 -
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs (2020).
51 -
Fluoroquinolone-3-carboxamide Amino Acid Conjugates: Synthesis, Antibacterial Properties And Molecular Modeling Studies (2021).
52 -
Controlling of Bacterial Virulence: Evaluation of Anti-Virulence Activities of Prazosin against Salmonella enterica (2022).
53 -
Hiring of the Anti-Quorum Sensing Activities of Hypoglycemic Agent Linagliptin to Alleviate the Pseudomonas aeruginosa Pathogenesis (2022).
54 -
Sodium Citrate Alleviates Virulence in Pseudomonas aeruginosa (2022).
55 -
Anti-Quorum Sensing Activities of Gliptins against Pseudomonas aeruginosa and Staphylococcus aureus (2022).
56 -
Human dihydrofolate reductase inhibition effect of 1-Phenylpyrazolo [3,4–d]pyrimidines: Synthesis, antitumor evaluation and molecular modeling study (2022).
57 -
Design, synthesis and antitumor evaluation of novel pyrazolo[3,4-d]pyrimidines incorporating different amino acid conjugates as potential DHFR inhibitors (2022).
58 -
Development of Isatin-Based Schiff Bases Targeting VEGFR-2 Inhibition: Synthesis, Characterization, Antiproliferative Properties, and QSAR Studies (2022).
59 -
Schiff bases as linker in the development of quinoline-sulfonamide hybrids as selective cancer-associated carbonic anhydrase isoforms IX/XII inhibitors: A new regioisomerism tactic (2022).
60 -
Drug repositioning: doxazosin attenuates the virulence factors and biofilm formation in Gram-negative bacteria (2023).
61 -
Synergistic Benefits: Exploring the Anti-Virulence Effects of Metformin/Vildagliptin Antidiabetic Combination against Pseudomonas aeruginosa via Controlling Quorum Sensing Systems (2023).
62 -
Exploitation of multi-walled carbon nanotubes/ Cu(II)-metal organic framework based glassy carbon electrode for the determination of orphenadrine citrate (2023).
63 -
Cilostazol is a promising anti-pseudomonal virulence drug by disruption of quorum sensing (2024).
64 -
Redirecting pantoprazole as a metallo-beta-lactamase inhibitor in carbapenem-resistant Klebsiella pneumoniae (2024).
Research Area
الكيمياء الطبية/ الصيدلية
الكيمياء العضوية
الكيمياء العضوية الصيدلية
جامعة المنصورة
جامعة الاسكندرية
جامعة القاهرة
جامعة سوهاج
جامعة الفيوم
جامعة بنها
جامعة دمياط
جامعة بورسعيد
جامعة حلوان
جامعة السويس
جامعة المنيا
جامعة دمنهور
جامعة المنوفية
جامعة أسوان
جامعة جنوب الوادى
جامعة قناة السويس
جامعة عين شمس
جامعة أسيوط
شراقوة | الشرقية بين ايديك
اخبار الشرقية - شراقوة | الشرقية بين ايديك
جامعة كفر الشيخ
جامعة السادات
جامعة طنطا
جامعة بنى سويف
