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Curriculum Vitae

Samar Saied Mahmoud Mohamed Elbaramawy

Faculty pharmacy - Department Medicinal Chemistry Department

Scientific degrees

BSc In NULL, [2009]
MSc In NULL, [2014]
PhD In NULL, [2018]

الحالة الوظيفية الحالية :

قائم بالعمل

Academic Jobs

معيد : 23/11/2009
Doctor Assisant : 6/5/2014
Doctor : 27/11/2018
استاذ مساعد لقب علمى : 28/1/2025

Publications

1 - Spectrophotometric determination of ranitidine hydrochloride and famotidine using 1,2- naphthoquinone-4-sulphonate (2013).

2 - Spectrophotometric determination of omeprazole sodium and rantidine hydrochloride using 2,4-dinitrofluorobenzene and 4-chloro-7-nitrobenz-2-oxa-1,3-diazole accompanied with a kinetic study (2014).

3 - RP-HPLC method for the simultaneous determination of omeprazole, tinidazole and doxycycline mixture in the presence of omeprazole and tinidazole degradation products (2014).

4 - Spectrophotometric determination of omeprazole via nitrosation reaction (2014).

5 - Validated spectophotometric determination of pantoprazole sodium in tablets using 2,4-dinitrofluorobenzene through nucleophilic substitution reaction (2014).

6 - Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach (2017).

7 - A homology model of Staphylococcus aureus phenylalanine tRNA synthetase: Active site analysis and docking interactions (2016).

8 - Design, synthesis and microbiological evaluation of novel compounds as potential Staphylococcus aureus phenylalanine tRNA synthetase inhibitors (2018).

9 - Characterization of the Anti-Biofilm and Anti-Quorum Sensing Activities of the β-Adrenoreceptor Antagonist Atenolol against Gram-Negative Bacterial Pathogens (2022).

10 - Silencing of Salmonella typhimurium Pathogenesis: Atenolol Acquires Efficient Anti-Virulence Activities (2022).

11 - Muting Bacterial Communication: Evaluation of Prazosin Anti-Quorum Sensing Activities against Gram-Negative Bacteria Pseudomonas aeruginosa, Proteus mirabilis, and Serratia marcescens (2022).

12 - Schiff bases as linker in the development of quinoline-sulfonamide hybrids as selective cancer-associated carbonic anhydrase isoforms IX/XII inhibitors: A new regioisomerism tactic (2022).

13 - Agathis robusta Bark Essential Oil Effectiveness against COVID-19: Chemical Composition, In Silico and In Vitro Approaches (2022).

14 - Agathis robusta Bark Extract Protects from Renal Ischemia-Reperfusion Injury: Phytochemical, In Silico and In Vivo Studies (2022).

15 - Targeting Mycobacterium tuberculosis: Synthesis, in vitro and in silico evaluation of novel N1-(benzo[d]oxazol-2-yl)-N4-arylidine compounds (2023).

16 - Design, synthesis, in vitro and in silico evaluation of novel substituted 1,2,4-triazole analogues as dual human VEGFR-2 and TB-InhA inhibitors (2023).

17 - Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation (2023).

18 - Drug repositioning: doxazosin attenuates the virulence factors and biofilm formation in Gram-negative bacteria (2023).

19 - Design and synthesis of novel uracil-linked Schiff bases as dual histone deacetylase type II/topoisomerase type I inhibitors with apoptotic potential (2023).

20 - Triple targeting of mutant EGFRL858R/T790M, COX-2, and 15-LOX: design and synthesis of novel quinazolinone tethered phenyl urea derivatives for anti-inflammatory and anticancer evaluation (2023).

21 - Different instrumental techniques for analysis of some gastrointestinal tract drugs (2024).

22 - Design and Synthesis of Novel Phenylalanine tRNA Synthetase Inhibitors as Potential Therapeutics for the Treatment of MRSA Infections (2024).

23 - Design and Synthesis of Novel Azoles-Containing Compounds for Biological Evaluation (2024).

24 - Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate (2023).

25 - Synergistic Benefits: Exploring the Anti-Virulence Effects of Metformin/Vildagliptin Antidiabetic Combination against Pseudomonas aeruginosa via Controlling Quorum Sensing Systems (2023).

26 - Exploitation of multi-walled carbon nanotubes/ Cu(II)-metal organic framework based glassy carbon electrode for the determination of orphenadrine citrate (2023).

27 - Casuarina glauca branchlets' extract as a potential treatment for ulcerative colitis: chemical composition, in silico and in vivo studies (2023).

28 - Chamaecyparis lawsoniana Leaf Essential Oil as a Potential Anticancer Agent: Experimental and Computational Studies (2023).

29 - Design and synthesis of uracil/thiouracil based quinoline scaffolds as topoisomerases I&II inhibitors for chemotherapy: A new hybrid navigator with DFT calculation (2023).

30 - Different methods for resolving overlapping UV spectra of combination medicinal dose forms of ciprofloxacin and metronidazole (2023).

31 - Developing a highly validated and sensitive HPLC method for simultaneous estimation of cefotaxime and paracetamol in pure and pharmaceutical preparations (2023).

32 - Drug repositioning: doxazosin attenuates the virulence factors and biofilm formation in Gram-negative bacteria (2023).

33 - Design and synthesis of novel uracil-linked Schiff bases as dual histone deacetylase type II/topoisomerase type I inhibitors with apoptotic potential (2023).

34 - Exploring Proteus mirabilis Methionine tRNA Synthetase Active Site: Homology Model Construction, Molecular Dynamics, Pharmacophore and Docking Validation (2023).

35 - Various techniques for resolving overlapping ultraviolet spectra of combination pharmaceutical dosage forms containing hydroxychloroquine and paracetamol (2024).

36 - Novel 2-[thio]acetamide linked quinazoline/1,2,4-triazole/chalcone hybrids: Design, synthesis, and anticancer activity as EGFR inhibitors and apoptotic inducers (2024).

37 - Instrumental analytical techniques for evaluating some anti-infective drugs in pharmaceutical products and biological fluids (2024).

38 - Utilization of zein nano-based system for promoting antibiofilm and anti-virulence activities of curcumin against Pseudomonas aeruginosa (2024).

Research Area