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Alsayed Mohamed Mansour Lashen

Faculty pharmacy - Department Medicinal Chemistry Department

BSc In NULL, [1975]
MSc In NULL, [1981]
PhD In NULL, [1986]

قائم بالعمل

Academic Jobs

معيد : 1/1/1976
Doctor Assisant : 5/11/1980
Doctor : 28/9/1986
Professor Assisant : 27/7/1993
Professor : 25/7/2000
Professor Emeritus : 1/8/2011

Publications

1 - Synthesisis Of Certain Condensed Pyrimidines

2 - Targeting methionyl tRNA synthetase: design, synthesis and antibacterial activity against Clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives (2016).

3 - Targeting methionyl t RNA synthetase: design ,synthesis and antibacterial activity against clostridium difficile of novel 3-biaryl-N-benzylpropan-1-amine derivatives (2016).

4 - Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4-Quinazolinone Derivatives (2017).

5 - Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach (2017).

6 - Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents (2016).

7 - Exploring the binding sites of Staphylococcus aureus phenylalanine tRNA synthetase: A homology model approach (2017).

8 - Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2- amines as Bcl-2 inhibitory anticancer agents (2016).

9 - Synthesis, Anticonvulsant Activity, and SAR Study of Novel 4-Quinazolinone Derivatives (2017).

10 - Design, synthesis and biological evaluation of novel quinazoline-2,4- diones conjugated with different amino acids as potential chitin synthase inhibitors (2018).

11 - Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2 (2020).

12 - Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2 (2020).

13 - Design and synthesis of novel quinazolinone–chalcone hybrids as potential apoptotic candidates targeting caspase-3 and PARP-1: in vitro, molecular docking, and SAR studies (2022).

14 - Adenine and benzimidazole-based mimics of REP-3123 as antibacterial agents against Clostridium difficile and Bacillus anthracis: design, synthesis and biological evaluation (2016).

15 - Design and Synthesis of Novel Phenylalanine tRNA Synthetase Inhibitors as Potential Therapeutics for the Treatment of MRSA Infections (2024).

Research Area